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CRAN - Package BOIN
Web4 BOIN: An R Package for Bayesian Optimal Interval Designs Start at the prespecified starting dose Treat a patient or a cohort of patients Stop the trial and select the MTD Yes Reach the maximum sample size No £ l e Compute ³ l d the DLT rate* at the current dose Within (l e, l d) Escalate the dose Retain the current dose http://odin.mdacc.tmc.edu/~yyuan/Software/BOIN/BOIN2.6_tutorial.pdf adp fire roll call
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WebNov 16, 2024 · BOIN12 differs from the recently proposed utility-based BOIN (U-BOIN) design in that U-BOIN is a two-stage design 41 for which the first stage performs dose escalation on the basis of toxicity, as in conventional phase I trials, and only the second stage uses the toxicity-efficacy trade-off for decision making. In contrast, BOIN12 is a … Web:exclamation: This is a read-only mirror of the CRAN R package repository. BOIN — Bayesian Optimal INterval (BOIN) Design for Single-Agent and Drug- Combination … WebR 包初学者指南. R 包是由社区开发(developed by the community)的功能(functions)和数据集(data sets)的集合。. 它们通过改进现有的基本 R 功能或通过添加新功能来提 … adp florida income calculator