High affinity copper uptake protein

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August undefined, 2024

Web27 de abr. de 2024 · In silico analysis has revealed three ferroxidase genes, namely CgFET3 (high affinity iron uptake; 70% similarity with ScFET3), ... Rydén, L.G.; Hunt, L.T. Evolution of protein complexity: The blue copper-containing oxidases and related proteins. J. Mol. Evol. 1993, 36, 41–66. Web21 de mar. de 2024 · High Affinity Copper Uptake Protein 1 3 4 Copper Transporter 1 3 4 Solute Carrier Family 31 (Copper Transporters), Member 1 3 Copper Transport 1 Homolog 3 External Ids for SLC31A1 Gene HGNC: 11016 NCBI Entrez Gene: 1317 Ensembl: ENSG00000136868 OMIM®: 603085 UniProtKB/Swiss-Prot: O15431 Previous HGNC …

The copper transporter CTR1 provides an essential function in

WebHigh-affinity, saturable copper transporter involved in dietary copper uptake. go to UniProt 3D viewer pLDDT corresponds to the model’s prediction of its score on the local … Web1 de abr. de 2014 · As previously mentioned, high-affinity Fe uptake at the plasma membrane depends in S. cerevisiae on Fet3 ferroxidase, which uses Cu as an indispensable cofactor for its activity. Therefore, Cu deficiency leads to impaired Fe transport in yeast, and consequently to multiple Fe-related symptoms [ 61 ]. cumberland mhidd

A Permease-Oxidase Complex Involved in High-Affinity Iron Uptake …

Web1 de out. de 2002 · High affinity copper uptake protein 1 Gene Slc31a1 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 196 Protein … Web30 de dez. de 2005 · High affinity copper binding by wild type PrP has been confirmed by the independent techniques indicating the presence of specific tight copper binding sites … WebProtein target information for High affinity copper uptake protein 1 (Norway rat). Find diseases associated with this biological target and compounds tested against it in … east stained glass patterns

Characterization of the Saccharomyces cerevisiae High …

O15431 - UniProt

High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais WebIt was shown that a gene, CTR1, encoded a multispanning plasma membrane protein that was specifically required for high affinity copper transport into yeast.The CTR1 gene product is a protein composed of 406 amino acid residues. A second high affinity copper uptake protein, encoded by the CTR3 gene, was subsequently identified. The two gene … east standard time to gmtWeb30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ … cumberland middle school

"WebCrystal structure of the high-affinity copper transporter Ctr1. PDB DOI: 10.2210/pdb6M97/pdb. Classification: TRANSPORT PROTEIN. Organism (s): Salmo salar, Escherichia coli. Expression System: Komagataella phaffii GS115. Mutation (s): Yes. Membrane Protein: Yes OPM PDBTM MemProtMD mpstruc. Deposited: 2024-08-22 … " - High affinity copper uptake protein

High affinity copper uptake protein

Nerve Growth Factor Peptides Bind Copper(II) with High Affinity: A ...

WebLOC100178573 high affinity copper uptake protein 1-like [ (vase tunicate)] Gene ID: 100178573, updated on 26-Oct-2024. Summary Other designations. high affinity ... WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562COPPER (I) IONZINC ION NCBI National Center forBiotechnology Information Search 6M98: Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu(I) Biological Unit for 6M98: trimeric; determined by author and by software (PISA)

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WebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … Web10 de abr. de 2024 · Abstract Heavy metal contamination impacts plant growth and productivity by causing damage at all levels of plant organization, making it one of the most significant abiotic stressors. This study evaluated the uptake and distribution of cadmium (Cd) and copper (Cu) in Solanum lycopersicum L. and identified the antioxidant enzyme …

Web12 de out. de 2012 · The Ctr1 gene encodes a multispanning plasma membrane protein of 460 amino acids and is a necessary factor in high affinity copper uptake and supplies copper for all known copper-dependent physiological processes (Georgatsou et al., 1997, Sinani et al., 2007, Nakagawa et al., 2010). WebProtein target information for High affinity copper uptake protein 1 (house mouse). Find diseases associated with this biological target and compounds tested against it in …

Web5 de abr. de 2024 · Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with … WebCopper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. Evolutionarily …

Web11 de abr. de 2024 · To investigate whether Met44 residue in COPT1 is also sufficient for copper acquisition, we converted Met44 to alanine in the full-length COPT1 protein, and transformed this mutant allele [COPT1(M44A)] into S. cerevisiae ctr1Δctr3Δ strain which lacks high affinity copper transporters CTR1 and CTR3 and cannot grow on …

WebThe redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. However, little is known … eaststandhibs.comWebCatalog FieldsAntigen: High affinity copper uptake protein 1Available to For-Profits: YesAntigen Species: HumanHybridoma Cells Available (Non-Profit): NoIsotype: MIgG2bDepositor: Clinical Proteomics Technologies for CancerHost Species: mouseAntigen Sequence: Positive Tested Species Reactivity: HumanDepositors Institution: National … cumberland metals case study pricingWebHigh affinity copper uptake protein 1 Alternative names Copper transporter 1 ( rCTR1) Liver regeneration-related protein LRRGT00200 Solute carrier family 31 member 1 … east stand box headingleyWebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function east stand headingley cricketWeb15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... east stanley cricket clubWebProtein High affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence … east stanley fish shopWebHigh affinity copper uptake protein 1 DrugBank Online with DrugBank on your side. High affinity copper uptake protein 1 Details Name High affinity copper uptake protein 1 Synonyms Copper transporter 1 COPT1 CTR1 hCTR1 Solute carrier family 31 member 1 Gene Name SLC31A1 Organism Humans Amino acid sequence cumberland middle school cumberland wi